IFN-Aging: Coupling Aging With Interferon Response

Chronic inflammation affects many diseases and conditions, including aging. Interferons are a part of the immune defense against viral infections. Paradoxically, various aging tissues and organs from mammalian hosts perpetually accumulate changes brought by interferon pathway activation. Herein, we...

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Detalles Bibliográficos
Autor principal: Cao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261325/
https://www.ncbi.nlm.nih.gov/pubmed/35821859
http://dx.doi.org/10.3389/fragi.2022.870489
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author Cao, Wei
author_facet Cao, Wei
author_sort Cao, Wei
collection PubMed
description Chronic inflammation affects many diseases and conditions, including aging. Interferons are a part of the immune defense against viral infections. Paradoxically, various aging tissues and organs from mammalian hosts perpetually accumulate changes brought by interferon pathway activation. Herein, we connote the mechanisms behind this phenomenon and discuss its implications in age-related pathology.
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spelling pubmed-92613252022-07-11 IFN-Aging: Coupling Aging With Interferon Response Cao, Wei Front Aging Aging Chronic inflammation affects many diseases and conditions, including aging. Interferons are a part of the immune defense against viral infections. Paradoxically, various aging tissues and organs from mammalian hosts perpetually accumulate changes brought by interferon pathway activation. Herein, we connote the mechanisms behind this phenomenon and discuss its implications in age-related pathology. Frontiers Media S.A. 2022-05-02 /pmc/articles/PMC9261325/ /pubmed/35821859 http://dx.doi.org/10.3389/fragi.2022.870489 Text en Copyright © 2022 Cao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Aging
Cao, Wei
IFN-Aging: Coupling Aging With Interferon Response
title IFN-Aging: Coupling Aging With Interferon Response
title_full IFN-Aging: Coupling Aging With Interferon Response
title_fullStr IFN-Aging: Coupling Aging With Interferon Response
title_full_unstemmed IFN-Aging: Coupling Aging With Interferon Response
title_short IFN-Aging: Coupling Aging With Interferon Response
title_sort ifn-aging: coupling aging with interferon response
topic Aging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261325/
https://www.ncbi.nlm.nih.gov/pubmed/35821859
http://dx.doi.org/10.3389/fragi.2022.870489
work_keys_str_mv AT caowei ifnagingcouplingagingwithinterferonresponse

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