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Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8(+) T Cells in Unexposed Individuals

Age is a major risk factor for COVID-19 severity, and T cells play a central role in anti-SARS-CoV-2 immunity. Because SARS-CoV-2-cross-reactive T cells have been detected in unexposed individuals, we investigated the age-related differences in pre-existing SARS-CoV-2-reactive T cells. SARS-CoV-2-re...

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Detalles Bibliográficos
Autores principales:	Jo, Norihide, Zhang, Rui, Ueno, Hideki, Yamamoto, Takuya, Weiskopf, Daniela, Nagao, Miki, Yamanaka, Shinya, Hamazaki, Yoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261342/ https://www.ncbi.nlm.nih.gov/pubmed/35822004 http://dx.doi.org/10.3389/fragi.2021.719342

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