Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88

The underlying mechanism by which MyD88 regulates the development of obesity, metainflammation, and insulin resistance (IR) remains unknown. Global deletion of MyD88 in high-fat diet (HFD)-fed mice resulted in increased weight gain, impaired glucose homeostasis, elevated Dectin-1 expression in adipo...

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Detalles Bibliográficos
Autores principales: Castoldi, Angela, Andrade-Oliveira, Vinicius, Aguiar, Cristhiane Favero, Amano, Mariane Tami, Lee, Jennifer, Miyagi, Marcelli Terumi, Teatin Latância, Marcela, Braga, Tarcio Teodoro, da Silva, Marina Burgos, Ignácio, Aline, Lima, Joanna Darck Carola Correia, Loures, Flavio V., Albuquerque, José Antonio T., Macêdo, Marina Barguil, Almeida, Rafael Ribeiro, Gaiarsa, Jonas W., Luévano-Martínez, Luis A., Belchior, Thiago, Hiyane, Meire Ioshie, Brown, Gordon D., Mori, Marcelo A., Hoffmann, Christian, Seelaender, Marília, Festuccia, Willian T., Moraes-Vieira, Pedro Manoel, Câmara, Niels Olsen Saraiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261359/
https://www.ncbi.nlm.nih.gov/pubmed/28614714
http://dx.doi.org/10.1016/j.celrep.2017.05.059

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