Diminished Pneumococcal-Specific CD4(+) T-Cell Response is Associated With Increased Regulatory T Cells at Older Age

Respiratory infection caused by Streptococcus pneumoniae is a leading cause of morbidity and mortality in older adults. Acquired CD4(+) T cell mechanism are essential for the protection against colonization and subsequent development of infections by S. pneumoniae. In this study, we hypothesized tha...

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Detalles Bibliográficos
Autores principales: He, Samantha W. J., van de Garde, Martijn D. B., Pieren, Daan K. J., Poelen, Martien C. M., Voß, Franziska, Abdullah, Mohammed R., Hammerschmidt, Sven, van Els, Cécile A. C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261371/
https://www.ncbi.nlm.nih.gov/pubmed/35822055
http://dx.doi.org/10.3389/fragi.2021.746295

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