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Differential Effects of 2-Deoxyglucose and Glucose Deprivation on 4-Hydroxynonenal Dependent Mitochondrial Dysfunction in Primary Neurons

Mitochondrial dysfunction and metabolic decline are prevalent features of aging and age-related disorders, including neurodegeneration. Neurodegenerative diseases are associated with a progressive loss of metabolic homeostasis. This pathogenic decline in metabolism is the result of several factors,...

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Detalles Bibliográficos
Autores principales:	Dodson, Matthew, Benavides, Gloria A., Darley-Usmar, Victor, Zhang, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261388/ https://www.ncbi.nlm.nih.gov/pubmed/35821809 http://dx.doi.org/10.3389/fragi.2022.812810

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