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Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8(+) EMRA T Cells During Type 2 Diabetes
Mitochondrial health and cellular metabolism can heavily influence the onset of senescence in T cells. CD8(+) EMRA T cells exhibit mitochondrial dysfunction and alterations to oxidative phosphorylation, however, the metabolic properties of senescent CD8(+) T cells from people living with type 2 diab...
Autores principales: | Callender, Lauren A., Carroll, Elizabeth C., Garrod-Ketchley, Conor, Schroth, Johannes, Bystrom, Jonas, Berryman, Victoria, Pattrick, Melanie, Campbell-Richards, Desiree, Hood, Gillian A., Hitman, Graham A., Finer, Sarah, Henson, Sian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261431/ https://www.ncbi.nlm.nih.gov/pubmed/35821991 http://dx.doi.org/10.3389/fragi.2021.681428 |
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