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The CBP-1/p300 Lysine Acetyltransferase Regulates the Heat Shock Response in C. elegans

The decline of proteostasis is a hallmark of aging that is, in part, affected by the dysregulation of the heat shock response (HSR), a highly conserved cellular response to proteotoxic stress in the cell. The heat shock transcription factor HSF-1 is well-studied as a key regulator of proteostasis, b...

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Detalles Bibliográficos
Autores principales: Barrett, Lindsey N., Westerheide, Sandy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261439/
https://www.ncbi.nlm.nih.gov/pubmed/35821825
http://dx.doi.org/10.3389/fragi.2022.861761