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INDY—From Flies to Worms, Mice, Rats, Non-Human Primates, and Humans

I’m Not Dead Yet (Indy) is a fly homologue of the mammalian SLC13A5 (mSLC13A5) plasma membrane citrate transporter, a key metabolic regulator and energy sensor involved in health, longevity, and disease. Reduction of Indy gene activity in flies, and its homologs in worms, modulates metabolism and ex...

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Detalles Bibliográficos
Autores principales: Mishra, Dushyant, Kannan, Kavitha, Meadows, Kali, Macro, Jacob, Li, Michael, Frankel, Stewart, Rogina, Blanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261455/
https://www.ncbi.nlm.nih.gov/pubmed/35822025
http://dx.doi.org/10.3389/fragi.2021.782162

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