Cargando…

Effect of 6,7-dimethoxy-2,2-dimethyl-2H-chromene (agerarin) on the recovery of filaggrin expression through targeting of Janus kinases in the inflammatory skin

Filaggrin (FLG) is a structural component of the stratum corneum that is essential for maintaining the barrier function of the skin and for the formation of natural moisturizing factors. 6,7-Dimethoxy-2,2-dimethyl-2H-chromene (Agerarin) is a bioactive compound derived from Ageratum houstonianum, a p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahn, Sung Shin, Lee, Young Han, Yeo, Hyunjin, Lee, Youngshim, Min, Do Sik, Lim, Yoongho, Shin, Soon Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taiwan Food and Drug Administration 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261804/ https://www.ncbi.nlm.nih.gov/pubmed/35696096 http://dx.doi.org/10.38212/2224-6614.1178

Ejemplares similares

The Natural Janus Kinase Inhibitor Agerarin Downregulates Interleukin-4-Induced PER2 Expression in HaCaT Keratinocytes
por: Lee, Jeong Yeon, et al.
Publicado: (2022)

FRA1:c-JUN:HDAC1 complex down-regulates filaggrin expression upon TNFα and IFNγ stimulation in keratinocytes
por: Ahn, Sung Shin, et al.
Publicado: (2022)

Agerarin, identified from Ageratum houstonianum, stimulates circadian CLOCK-mediated aquaporin-3 gene expression in HaCaT keratinocytes
por: Shin, Soon Young, et al.
Publicado: (2017)

4-Hydroxy-3-[(4-hydroxy-6,7-dimethyl-2-oxo-2H-chromen-3-yl)(4-oxo-4H-chromen-3-yl)methyl]-6,7-dimethyl-2H-chromen-2-one
por: Asad, Mohammad, et al.
Publicado: (2010)

3-Acetyl-4-hydroxy-6,7-dimethyl-2H-chromen-2-one
por: Asad, Mohammad, et al.
Publicado: (2010)

β-Caryophyllene Ameliorates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis through the Downregulation of Mitogen-Activated Protein Kinase/EGR1/TSLP Signaling Axis
por: Ahn, Sung Shin, et al.
Publicado: (2022)

Inhibitory Effect of Synthetic Flavone Derivatives on Pan-Aurora Kinases: Induction of G2/M Cell-Cycle Arrest and Apoptosis in HCT116 Human Colon Cancer Cells
por: Shin, Soon Young, et al.
Publicado: (2018)

Chrysin Inhibits NF-κB-Dependent CCL5 Transcription by Targeting IκB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment
por: Yeo, Hyunjin, et al.
Publicado: (2020)

Chrysin Inhibits TNFα-Induced TSLP Expression through Downregulation of EGR1 Expression in Keratinocytes
por: Yeo, Hyunjin, et al.
Publicado: (2021)

Saikosaponin A and Saikosaponin C Reduce TNF-α-Induced TSLP Expression through Inhibition of MAPK-Mediated EGR1 Expression in HaCaT Keratinocytes
por: Ahn, Sung Shin, et al.
Publicado: (2022)

5,7-Dimethoxy-2-phenyl-4H-chromen-4-one
por: Nallasivam, Angannan, et al.
Publicado: (2009)

3-Hydroxymethyl-6,8-dimethoxy-2H-chromen-2-one
por: Wei, Mei-yan, et al.
Publicado: (2008)

8-Iodo-5,7-dimethoxy-4-methyl-2H-chromen-2-one
por: Pereira Silva, P. S., et al.
Publicado: (2011)

1-(2-Fluorophenyl)-6,7-dimethoxyisochroman
por: Saeed, Aamer, et al.
Publicado: (2009)

6,7-Dimethoxy-2,4-diphenylquinoline
por: Prabhuswamy, M., et al.
Publicado: (2014)

2,2′-Dimethoxybiphenyl
por: Nakaema, Kosuke, et al.
Publicado: (2008)

5,5′-Dimethoxy-2,2′-[2,2-dimethylpropane-1,3-diylbis(nitrilomethylidyne)]diphenol
por: Yeap, Chin Sing, et al.
Publicado: (2008)

6,6′-Dimethoxy-2,2′-[2,2-dimethylpropane-1,3-diylbis(nitrilomethylidyne)]diphenol
por: Yeap, Chin Sing, et al.
Publicado: (2008)

4,4′-Dimethoxy-2,2′-[2,2-dimethylpropane-1,3-diylbis(nitrilomethanylylidene)]diphenol
por: Kargar, Hadi, et al.
Publicado: (2011)

2-(5,7-Dimethoxy-4-oxo-4H-chromen-2-yl)phenyl 4-toluenesulfonate
por: Ramachandran, G., et al.
Publicado: (2008)

Redetermination of 6,6′-dimethoxy-2,2′-[hexane-1,6-diylbis(nitrilodimethylidyne)]diphenol
por: Tabatabaee, M., et al.
Publicado: (2011)

{5,5′-Dimethoxy-2,2′-[2,2-dimethylpropane-1,3-diylbis(nitrilomethanylylidene)]diphenolato}palladium(II)
por: Che Soh, Siti Kamilah, et al.
Publicado: (2012)

{4,4′-Dimethoxy-2,2′-[2,2-dimethylpropane-1,3-diylbis(nitrilomethylidyne)]diphenolato}nickel(II)
por: Montazerozohori, Morteza, et al.
Publicado: (2009)

1-(5-Hydroxy-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethan-1-one
por: Liu, Bingjing, et al.
Publicado: (2010)

Dimethylammonium 2-[(2-oxo-2H-chromen-7-yl)oxy]acetate
por: Dong, Feng-Xia
Publicado: (2011)

Crystal structure of (E)-4,6-dimethoxy-2-(4-methoxystyryl)-3-methylbenzaldehyde
por: Ahn, Seunghyun, et al.
Publicado: (2015)

{4,4′-Dimethoxy-2,2′-[2,2-dimethylpropane-1,3-diylbis(nitrilomethanylylidene)]diphenolato}copper(II) monohydrate
por: Ganji, Fatemeh, et al.
Publicado: (2012)

6,7-Dimethoxy-1,4-anthraquinone
por: Kitamura, Chitoshi, et al.
Publicado: (2008)

5,5′-Dimethoxy-2,2′-[4,5-dimethyl-o-phenylenebis(nitrilomethylidyne)]diphenol
por: Kargar, Hadi, et al.
Publicado: (2010)

5-[(3,4-Dimethoxybenzyl)aminomethylene]-2,2-dimethyl-1,3-dioxane-4,6-dione
por: Li, Rui, et al.
Publicado: (2009)

Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation
por: Donovan, Mark, et al.
Publicado: (2020)

Discovery of 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenoxy)-chromen-4-one with Lipid Lowering Effects in Hepatocytes
por: Chang, Yi-Han, et al.
Publicado: (2022)

6,6′-Dimethoxy-2,2′-[4,5-dimethyl-o-phenylenebis(nitrilomethylidyne)]diphenol monohydrate
por: Kargar, Hadi, et al.
Publicado: (2010)

3,3′-Dimethoxy-2,2′-[(4,5-dimethyl-o-phenylene)bis(nitrilomethanylylidene)]diphenol
por: Sahraei, Atefeh, et al.
Publicado: (2011)

2-[(2,4-Dimethylphenyl)iminomethyl]-3,5-dimethoxyphenol
por: Tanak, Hasan, et al.
Publicado: (2009)

Crystal structure of 2-(2,3-dimethoxynaphthalen-1-yl)-3-hydroxy-6-methoxy-4H-chromen-4-one
por: Ahn, Seunghyun, et al.
Publicado: (2015)

A Novel Synthetic Compound (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile Inhibits TNFα-Induced MMP9 Expression via EGR-1 Downregulation in MDA-MB-231 Human Breast Cancer Cells
por: Jeong, Munki, et al.
Publicado: (2020)

{6,6′-Dimethoxy-2,2′-[2,2-dimethylpropane-1,3-diylbis(nitrilomethylidyne)]diphenolato}nickel(II) 1.78-hydrate
por: Yeap, Chin Sing, et al.
Publicado: (2009)

{6,6′-Dimethoxy-2,2′-[ethane-1,2-diylbis(nitrilomethanylylidene)]diphenolato}nickel(II) dimethylformamide monosolvate
por: Ayikoé, Kouassi, et al.
Publicado: (2011)

Crystal structure of 2-(3,4-dimethoxyphenyl)-3-hydroxy-4H-chromen-4-one
por: Yoo, Jin Sil, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_q8mpp7h84ukeujjlo6om5i8jkb