Impact of the temperature on the interactions between common variants of the SARS-CoV-2 receptor binding domain and the human ACE2

Several key mutations in the Spike protein receptor binding domain (RBD) have been identified to influence its affinity for the human Angiotensin-Converting Enzyme 2 (ACE2). Here, we perform a comparative study of the ACE2 binding to the wild type (Wuhan) RBD and some of its variants: Alpha B.1.1.7,...

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Detalles Bibliográficos
Autores principales: Forest-Nault, Catherine, Koyuturk, Izel, Gaudreault, Jimmy, Pelletier, Alex, L’Abbé, Denis, Cass, Brian, Bisson, Louis, Burlacu, Alina, Delafosse, Laurence, Stuible, Matthew, Henry, Olivier, De Crescenzo, Gregory, Durocher, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261887/
https://www.ncbi.nlm.nih.gov/pubmed/35798770
http://dx.doi.org/10.1038/s41598-022-15215-5

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