Cargando…

Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis

The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign...

Descripción completa

Detalles Bibliográficos
Autores principales: de Sousa, André Luca Araujo, de Almeida, Wanderson Carvalho, de Pinho Mendes, Jean, Martins Montalli, Victor Angelo, Pinto, Antonione Santos Bezerra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262114/
https://www.ncbi.nlm.nih.gov/pubmed/35821721
http://dx.doi.org/10.15644/asc56/2/9
_version_ 1784742421799632896
author de Sousa, André Luca Araujo
de Almeida, Wanderson Carvalho
de Pinho Mendes, Jean
Martins Montalli, Victor Angelo
Pinto, Antonione Santos Bezerra
author_facet de Sousa, André Luca Araujo
de Almeida, Wanderson Carvalho
de Pinho Mendes, Jean
Martins Montalli, Victor Angelo
Pinto, Antonione Santos Bezerra
author_sort de Sousa, André Luca Araujo
collection PubMed
description The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth.
format Online
Article
Text
id pubmed-9262114
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association
record_format MEDLINE/PubMed
spelling pubmed-92621142022-07-11 Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis de Sousa, André Luca Araujo de Almeida, Wanderson Carvalho de Pinho Mendes, Jean Martins Montalli, Victor Angelo Pinto, Antonione Santos Bezerra Acta Stomatol Croat Case Report The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth. University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association 2022-06 /pmc/articles/PMC9262114/ /pubmed/35821721 http://dx.doi.org/10.15644/asc56/2/9 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.
spellingShingle Case Report
de Sousa, André Luca Araujo
de Almeida, Wanderson Carvalho
de Pinho Mendes, Jean
Martins Montalli, Victor Angelo
Pinto, Antonione Santos Bezerra
Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis
title Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis
title_full Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis
title_fullStr Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis
title_full_unstemmed Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis
title_short Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis
title_sort melanotic neuroectodermal tumor of infancy: the use of immunohistochemical analysis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262114/
https://www.ncbi.nlm.nih.gov/pubmed/35821721
http://dx.doi.org/10.15644/asc56/2/9
work_keys_str_mv AT desousaandrelucaaraujo melanoticneuroectodermaltumorofinfancytheuseofimmunohistochemicalanalysis
AT dealmeidawandersoncarvalho melanoticneuroectodermaltumorofinfancytheuseofimmunohistochemicalanalysis
AT depinhomendesjean melanoticneuroectodermaltumorofinfancytheuseofimmunohistochemicalanalysis
AT martinsmontallivictorangelo melanoticneuroectodermaltumorofinfancytheuseofimmunohistochemicalanalysis
AT pintoantonionesantosbezerra melanoticneuroectodermaltumorofinfancytheuseofimmunohistochemicalanalysis