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Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis
The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262114/ https://www.ncbi.nlm.nih.gov/pubmed/35821721 http://dx.doi.org/10.15644/asc56/2/9 |
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author | de Sousa, André Luca Araujo de Almeida, Wanderson Carvalho de Pinho Mendes, Jean Martins Montalli, Victor Angelo Pinto, Antonione Santos Bezerra |
author_facet | de Sousa, André Luca Araujo de Almeida, Wanderson Carvalho de Pinho Mendes, Jean Martins Montalli, Victor Angelo Pinto, Antonione Santos Bezerra |
author_sort | de Sousa, André Luca Araujo |
collection | PubMed |
description | The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth. |
format | Online Article Text |
id | pubmed-9262114 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-92621142022-07-11 Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis de Sousa, André Luca Araujo de Almeida, Wanderson Carvalho de Pinho Mendes, Jean Martins Montalli, Victor Angelo Pinto, Antonione Santos Bezerra Acta Stomatol Croat Case Report The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth. University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association 2022-06 /pmc/articles/PMC9262114/ /pubmed/35821721 http://dx.doi.org/10.15644/asc56/2/9 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License. |
spellingShingle | Case Report de Sousa, André Luca Araujo de Almeida, Wanderson Carvalho de Pinho Mendes, Jean Martins Montalli, Victor Angelo Pinto, Antonione Santos Bezerra Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis |
title | Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis |
title_full | Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis |
title_fullStr | Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis |
title_full_unstemmed | Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis |
title_short | Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis |
title_sort | melanotic neuroectodermal tumor of infancy: the use of immunohistochemical analysis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262114/ https://www.ncbi.nlm.nih.gov/pubmed/35821721 http://dx.doi.org/10.15644/asc56/2/9 |
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