CYP11A1-derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomas

Hydroxyderivatives of vitamin D3, including classical 1,25(OH)(2)D3 and novel CYP11A1-derived hydroxyderivatives, exert their biological activity by acting as agonists on the vitamin D receptor (VDR) and inverse agonists on retinoid-related orphan receptors (ROR)α and γ. The anti-cancer activities o...

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Detalles Bibliográficos
Autores principales: Slominski, Andrzej T., Brożyna, Anna A., Kim, Tae-Kang, Elsayed, Mahmoud M., Janjetovic, Zorica, Qayyum, Shariq, Slominski, Radomir M., Oak, Allen S.W., Li, Changzhao, Podgorska, Ewa, Li, Wei, Jetten, Anton M., Tuckey, Robert C., Tang, Edith K.Y., Elmets, Craig, Athar, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262157/
https://www.ncbi.nlm.nih.gov/pubmed/35775377
http://dx.doi.org/10.3892/ijo.2022.5386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262157/
https://www.ncbi.nlm.nih.gov/pubmed/35775377
http://dx.doi.org/10.3892/ijo.2022.5386

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