Interaction of immune checkpoint PD-1 and chemokine receptor 4 (CXCR4) promotes a malignant phenotype in pancreatic cancer cells

Despite recent therapeutic advances, pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease with limited therapeutic options. Immune checkpoint inhibitors (ICIs) have demonstrated promising results in many cancers, but thus far have yielded little clinical benefit in PDAC. Based on re...

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Detalles Bibliográficos
Autores principales: Harper, Megan M., Lin, Miranda, Cavnar, Michael J., Pandalai, Prakash K., Patel, Reema A., Gao, Mei, Kim, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262213/
https://www.ncbi.nlm.nih.gov/pubmed/35797269
http://dx.doi.org/10.1371/journal.pone.0270832

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