The intestinal microbial metabolite nicotinamide n-oxide prevents herpes simplex encephalitis via activating mitophagy in microglia

Herpes simplex encephalitis (HSE), a complication of herpes simplex virus type I (HSV-1) infection causes neurological disorder or even death in immunocompromised adults and newborns. However, the intrinsic factors controlling the HSE outcome remain unclear. Here, we show that HSE mice exhibit gut m...

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Detalles Bibliográficos
Autores principales: Li, Feng, Wang, Yiliang, Song, Xiaowei, Wang, Zhaoyang, Jia, Jiaoyan, Qing, Shurong, Huang, Lianzhou, Wang, Yuan, Wang, Shuai, Ren, Zhe, Zheng, Kai, Wang, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262364/
https://www.ncbi.nlm.nih.gov/pubmed/35793266
http://dx.doi.org/10.1080/19490976.2022.2096989

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