Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma

Structural discovery of guanine nucleotide exchange factor (GEF) protein complexes is likely to become increasingly relevant with the development of new therapeutics targeting small GTPases and development of new classes of small molecules that inhibit protein‐protein interactions. Syx (also known a...

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Detalles Bibliográficos
Autores principales: Boyd, Ryan J., Olson, Tien L., Zook, James D., Stein, Derek, Aceves, Manuel, Lin, Wan‐Hsin, Craciunescu, Felicia M., Hansen, Debra T., Anastasiadis, Panos Z., Singharoy, Abhishek, Fromme, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262375/
https://www.ncbi.nlm.nih.gov/pubmed/35639414
http://dx.doi.org/10.1096/fj.202101808RR

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