Cargando…

Host cell RecA activates a mobile element-encoded mutagenic DNA polymerase

Homologs of the mutagenic Escherichia coli DNA polymerase V (pol V) are encoded by numerous pathogens and mobile elements. We have used Rum pol (RumA′(2)B), from the integrative conjugative element (ICE), R391, as a model mobile element-encoded polymerase (MEPol). The highly mutagenic Rum pol is tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Ojha, Debika, Jaszczur, Malgorzata M, Sikand, Adhirath, McDonald, John P, Robinson, Andrew, van Oijen, Antoine M, Mak, Chi H, Pinaud, Fabien, Cox, Michael M, Woodgate, Roger, Goodman, Myron F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262582/
https://www.ncbi.nlm.nih.gov/pubmed/35736210
http://dx.doi.org/10.1093/nar/gkac515