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Identification of flexible Pif1–DNA interactions and their impacts on enzymatic activities
Flexible regions in biomolecular complexes, although crucial to understanding structure–function relationships, are often unclear in high-resolution crystal structures. In this study, we showed that single-molecule techniques, in combination with computational modeling, can characterize dynamic conf...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262596/ https://www.ncbi.nlm.nih.gov/pubmed/35748877 http://dx.doi.org/10.1093/nar/gkac529 |