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Identification of flexible Pif1–DNA interactions and their impacts on enzymatic activities

Flexible regions in biomolecular complexes, although crucial to understanding structure–function relationships, are often unclear in high-resolution crystal structures. In this study, we showed that single-molecule techniques, in combination with computational modeling, can characterize dynamic conf...

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Detalles Bibliográficos
Autores principales:	Li, Jinghua, Ma, Jianbing, Kumar, Vikash, Fu, Hang, Xu, Chunhua, Wang, Shuang, Jia, Qi, Fan, Qinkai, Xi, Xuguang, Li, Ming, Liu, Haiguang, Lu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262596/ https://www.ncbi.nlm.nih.gov/pubmed/35748877 http://dx.doi.org/10.1093/nar/gkac529

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