PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing

DICER1 syndrome is a cancer pre-disposition disorder caused by mutations that disrupt the function of DICER1 in miRNA processing. Studying the molecular, cellular and oncogenic effects of these mutations can reveal novel mechanisms that control cell homeostasis and tumor biology. Here, we conduct th...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajasekaran, Swetha, Khan, Eshan, Ching, Samuel R, Khan, Misbah, Siddiqui, Jalal K, Gradia, Daniela F, Lin, Chenyu, Bouley, Stephanie J, Mercadante, Dayna L, Manning, Amity L, Gerber, André P, Walker, James A, Miles, Wayne O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262620/
https://www.ncbi.nlm.nih.gov/pubmed/35736218
http://dx.doi.org/10.1093/nar/gkac499

Ejemplares similares

Ejemplares similares