Humoral and cellular immune response levels at a 1-year follow-up after mild COVID-19

The primary objective of this study was to establish a 1-year follow-up of patients after mild COVID-19 with no or only short-term detection of antibodies shortly after disease. At 1 year after disease, cellular memory against SARS-CoV-2, as measured by IFN-γ release by T cells, was detected in 76%...

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Detalles Bibliográficos
Autores principales: Flieder, Tobias, Fischer, Bastian, von Bargen, Katharina, Peter, Andreas, Knabbe, Cornelius, Birschmann, Ingvild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Guidelines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262650/
https://www.ncbi.nlm.nih.gov/pubmed/35896052
http://dx.doi.org/10.1016/j.jcv.2022.105236
Descripción
Sumario:The primary objective of this study was to establish a 1-year follow-up of patients after mild COVID-19 with no or only short-term detection of antibodies shortly after disease. At 1 year after disease, cellular memory against SARS-CoV-2, as measured by IFN-γ release by T cells, was detected in 76% (38/50) of participants. The data suggest that even if antibody levels decline after the primary infection has resolved, a cellular immune response may be detectable for longer.

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