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Short-Chain Fatty Acids Attenuate Renal Fibrosis and Enhance Autophagy of Renal Tubular Cells in Diabetic Mice Through the HDAC2/ULK1 Axis

BACKGROUND: This study investigated the effect of short-chain fatty acids (SCFAs) on diabetes in a mouse model. METHODS: Autophagy in Akita mice and streptozocin (STZ)-induced diabetic C57BL/6 mice was determined by Western blots and immunohistochemistry (IHC). Western blots, IHC, hematoxylin and eo...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoying, Wang, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262686/
https://www.ncbi.nlm.nih.gov/pubmed/35574586
http://dx.doi.org/10.3803/EnM.2021.1336