Cargando…
Single-cell transcriptional profiling of murine conjunctival immune cells reveals distinct populations expressing homeostatic and regulatory genes
Immune cells in the exposed conjunctiva mucosa defend against environmental and microbial stresses. Expression profiling by single-cell RNA sequencing was performed to identify conjunctival immune cell populations expressing homeostatic and regulatory genes. Fourteen distinct clusters were identifie...
Autores principales: | Alam, Jehan, Yazdanpanah, Ghasem, Ratnapriya, Rinki, Borcherding, Nicholas, de Paiva, Cintia S., Li, DeQuan, Pflugfelder, Stephen C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262780/ https://www.ncbi.nlm.nih.gov/pubmed/35361907 http://dx.doi.org/10.1038/s41385-022-00507-w |
Ejemplares similares
-
IL-17 Producing Lymphocytes Cause Dry Eye and Corneal Disease With Aging in RXRα Mutant Mouse
por: Alam, Jehan, et al.
Publicado: (2022) -
Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis
por: Alam, Jehan, et al.
Publicado: (2021) -
Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model
por: Yu, Zhiyuan, et al.
Publicado: (2023) -
Severity of Sjögren’s Syndrome Keratoconjunctivitis Sicca Increases with Increased Percentage of Conjunctival Antigen-Presenting Cells
por: Pflugfelder, Stephen C., et al.
Publicado: (2018) -
Retinoid Regulation of Ocular Surface Innate Inflammation
por: Alam, Jehan, et al.
Publicado: (2021)