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Pyrimethamine inhibits cell growth by inducing cell senescence and boosting CD8(+) T-cell mediated cytotoxicity in colorectal cancer

BACKGROUND: The emergence of nonresponse or resistance to traditional chemotherapeutic agents is one of the main challenges of colorectal cancer (CRC) therapies. Thus, novel therapeutic drugs that can improve the clinical outcomes of CRC patients are urgently needed. The purpose of this study was to...

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Detalles Bibliográficos
Autores principales:	Dong, Haiyan, Hu, Limei, Li, Weiqian, Shi, Mengchen, He, Lingyuan, Wang, Chen, Hu, Yijia, Wang, Huihui, Wen, Chuangyu, Liu, Huanliang, Yang, Xiangling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262800/ https://www.ncbi.nlm.nih.gov/pubmed/35262820 http://dx.doi.org/10.1007/s11033-022-07262-y

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