Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing

A limited number of cell lines have fueled the majority of preclinical prostate cancer research, but their genomes remain incompletely characterized. Here, we utilized whole-genome linked-read sequencing for comprehensive characterization of phased mutations and rearrangements in the most commonly u...

Descripción completa

Detalles Bibliográficos
Autores principales: Pham, Minh-Tam, Gupta, Anuj, Gupta, Harshath, Vaghasia, Ajay, Skaist, Alyza, Garrison, McKinzie A., Coulter, Jonathan B., Haffner, Michael C., Zheng, S. Lilly, Xu, Jianfeng, DeStefano Shields, Christina, Isaacs, William B., Wheelan, Sarah J., Nelson, William G., Yegnasubramanian, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Rapid Impact
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262859/
https://www.ncbi.nlm.nih.gov/pubmed/35452513
http://dx.doi.org/10.1158/1541-7786.MCR-21-0683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262859/
https://www.ncbi.nlm.nih.gov/pubmed/35452513
http://dx.doi.org/10.1158/1541-7786.MCR-21-0683

Ejemplares similares