Circulating N-Acetylaspartate does not track brain NAA concentrations, cognitive function or features of small vessel disease in humans

N-acetylaspartate (NAA) is the second most abundant metabolite in the human brain; although it is assumed to be a proxy for a neuronal marker, its function is not fully elucidated. NAA is also detectable in plasma, but its relation to cerebral NAA levels, cognitive performance, or features of cerebr...

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Detalles Bibliográficos
Autores principales: Rebelos, Eleni, Daniele, Giuseppe, Campi, Beatrice, Saba, Alessandro, Koskensalo, Kalle, Ihalainen, Jukka, Saukko, Ekaterina, Nuutila, Pirjo, Backes, Walter H., Jansen, Jacobus F. A., Dagnelie, Pieter C., Köhler, Sebastian, de Galan, Bastiaan E., van Sloten, Thomas T., Stehouwer, Coen D. A., Ferrannini, Ele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262942/
https://www.ncbi.nlm.nih.gov/pubmed/35798828
http://dx.doi.org/10.1038/s41598-022-15670-0

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