Downregulation of Neurofilament Light Chain Expression in Human Neuronal-Glial Cell Co-Cultures by a Microbiome-Derived Lipopolysaccharide-Induced miRNA-30b-5p

Microbiome-derived Gram-negative bacterial lipopolysaccharide (LPS) has been shown by multiple laboratories to reside within Alzheimer's disease (AD)-affected neocortical and hippocampal neurons. LPS and other pro-inflammatory stressors strongly induce a defined set of NF-kB (p50/p65)-sensitive...

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Detalles Bibliográficos
Autores principales: Pogue, Aileen I., Jaber, Vivian R., Sharfman, Nathan M., Zhao, Yuhai, Lukiw, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263091/
https://www.ncbi.nlm.nih.gov/pubmed/35812116
http://dx.doi.org/10.3389/fneur.2022.900048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263091/
https://www.ncbi.nlm.nih.gov/pubmed/35812116
http://dx.doi.org/10.3389/fneur.2022.900048

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