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Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis

Epithelial alarmins are gaining interest as therapeutic targets for chronic inflammation. The nuclear alarmin interleukin-33 (IL-33) is upregulated in the colonic mucosa of acute ulcerative colitis (UC) and may represent an early instigator of the inflammatory cascade. However, it is not clear what...

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Detalles Bibliográficos
Autores principales: Gundersen, Mona Dixon, Larsen, Kenneth Bowitz, Johnsen, Kay Martin, Goll, Rasmus, Florholmen, Jon, Haraldsen, Guttorm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263100/
https://www.ncbi.nlm.nih.gov/pubmed/35798804
http://dx.doi.org/10.1038/s41598-022-15573-0