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Nanoscale organization of two-dimensional multimeric pMHC reagents with DNA origami for CD8(+) T cell detection

Peptide-MHC (pMHC) multimers have excelled in the detection of antigen-specific T cells and have allowed phenotypic analysis using other reagents, but their use for detection of low-affinity T cells remains a challenge. Here we develop a multimeric T cell identifying reagent platform using two-dimen...

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Detalles Bibliográficos
Autores principales:	Sun, Yueyang, Yan, Lu, Sun, Jiajia, Xiao, Mingshu, Lai, Wei, Song, Guangqi, Li, Li, Fan, Chunhai, Pei, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263106/ https://www.ncbi.nlm.nih.gov/pubmed/35798752 http://dx.doi.org/10.1038/s41467-022-31684-8

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