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Cannabinoid CB(1) receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice

Cannabinoids are known to modulate oligodendrogenesis and developmental CNS myelination. However, the cell-autonomous action of these compounds on oligodendroglial cells in vivo, and the molecular mechanisms underlying these effects have not yet been studied. Here, by using oligodendroglial precurso...

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Detalles Bibliográficos
Autores principales: Sánchez-de la Torre, Aníbal, Aguado, Tania, Huerga-Gómez, Alba, Santamaría, Silvia, Gentile, Antonietta, Chara, Juan Carlos, Matute, Carlos, Monory, Krisztina, Mato, Susana, Guzmán, Manuel, Lutz, Beat, Galve-Roperh, Ismael, Palazuelos, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263142/
https://www.ncbi.nlm.nih.gov/pubmed/35798697
http://dx.doi.org/10.1038/s41419-022-05032-z