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Cannabinoid CB(1) receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice
Cannabinoids are known to modulate oligodendrogenesis and developmental CNS myelination. However, the cell-autonomous action of these compounds on oligodendroglial cells in vivo, and the molecular mechanisms underlying these effects have not yet been studied. Here, by using oligodendroglial precurso...
Autores principales: | Sánchez-de la Torre, Aníbal, Aguado, Tania, Huerga-Gómez, Alba, Santamaría, Silvia, Gentile, Antonietta, Chara, Juan Carlos, Matute, Carlos, Monory, Krisztina, Mato, Susana, Guzmán, Manuel, Lutz, Beat, Galve-Roperh, Ismael, Palazuelos, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263142/ https://www.ncbi.nlm.nih.gov/pubmed/35798697 http://dx.doi.org/10.1038/s41419-022-05032-z |
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