Cargando…

TET1 dioxygenase is required for FOXA2-associated chromatin remodeling in pancreatic beta-cell differentiation

Existing knowledge of the role of epigenetic modifiers in pancreas development has exponentially increased. However, the function of TET dioxygenases in pancreatic endocrine specification remains obscure. We set out to tackle this issue using a human embryonic stem cell (hESC) differentiation system...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jianfang, Wu, Xinwei, Ke, Jie, Lee, Minjung, Lan, Qingping, Li, Jia, Yu, Jianxiu, Huang, Yun, Sun, De-Qiang, Xie, Ruiyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263144/ https://www.ncbi.nlm.nih.gov/pubmed/35798741 http://dx.doi.org/10.1038/s41467-022-31611-x

Ejemplares similares

Decoding the role of TET family dioxygenases in lineage specification
por: Wu, Xinwei, et al.
Publicado: (2018)

The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH
por: Wang, Ranran, et al.
Publicado: (2015)

FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation
por: Lee, Kihyun, et al.
Publicado: (2019)

Whole‐genome analysis of TET dioxygenase function in regulatory T cells
por: Yue, Xiaojing, et al.
Publicado: (2021)

Foxa1 and Foxa2 Are Required for Formation of the Intervertebral Discs
por: Maier, Jennifer A., et al.
Publicado: (2013)

Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling
por: Lee, Minjung, et al.
Publicado: (2017)

TET family dioxygenases and DNA demethylation in stem cells and cancers
por: An, Jungeun, et al.
Publicado: (2017)

Role of TET dioxygenases in the regulation of both normal and pathological hematopoiesis
por: Joshi, Kanak, et al.
Publicado: (2022)

Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase
por: Wojciechowski, Marek, et al.
Publicado: (2014)

DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation
por: Chen, Guo-Dong, et al.
Publicado: (2023)

FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function
por: Yang, Yeqing A., et al.
Publicado: (2016)

Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance
por: Domanskyi, Andrii, et al.
Publicado: (2014)

Role of TET Dioxygenases and DNA Hydroxymethylation in Bisphenols-Stimulated Proliferation of Breast Cancer Cells
por: Li, Zhe, et al.
Publicado: (2020)

Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA
por: Hashimoto, Hideharu, et al.
Publicado: (2015)

Intrinsic and Extrinsic Connections of Tet3 Dioxygenase with CXXC Zinc Finger Modules
por: Liu, Nan, et al.
Publicado: (2013)

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA
por: Hashimoto, Hideharu, et al.
Publicado: (2013)

TET2 mutations as a part of DNA dioxygenase deficiency in myelodysplastic syndromes
por: Gurnari, Carmelo, et al.
Publicado: (2022)

Plastrum Testudinis Extracts Promote NSC Differentiation into Dopaminergic Neuron by Regulating the Interaction of TET1 and FoxA2
por: Zhong, Jun, et al.
Publicado: (2020)

Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns
por: Adam, Sabrina, et al.
Publicado: (2022)

Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE(−/−) mice
por: Peng, Juan, et al.
Publicado: (2016)

Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia
por: Guan, Yihong, et al.
Publicado: (2022)

Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency
por: Elsayed, Ahmed K., et al.
Publicado: (2021)

FoxA factors: the chromatin key and doorstop essential for liver development and function
por: Heslop, James A., et al.
Publicado: (2020)

Role of DNA dioxygenase Ten-Eleven translocation 3 (TET3) in rheumatoid arthritis progression
por: Kawabe, Akio, et al.
Publicado: (2022)

Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer
por: Gao, Shuai, et al.
Publicado: (2020)

Different chromatin-scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2
por: Lerner, Jonathan, et al.
Publicado: (2023)

Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Oxidizing and Reading 5-Methylcytosine
por: Lin, Tzu-Chen, et al.
Publicado: (2022)

Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
por: Wang, Jing, et al.
Publicado: (2017)

hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma
por: Xu, Lei, et al.
Publicado: (2023)

Phage-encoded ten-eleven translocation dioxygenase (TET) is active in C5-cytosine hypermodification in DNA
por: Burke, Evan J., et al.
Publicado: (2021)

Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development
por: Fang, Shaohai, et al.
Publicado: (2019)

Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility
por: Lio, Chan-Wang, et al.
Publicado: (2016)

Neuronal IFN-beta–induced PI3K/Akt-FoxA1 signalling is essential for generation of FoxA1(+)T(reg) cells
por: Liu, Yawei, et al.
Publicado: (2017)

Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2
por: Cernilogar, Filippo M, et al.
Publicado: (2019)

Corrigendum: Neuronal IFN-beta–induced PI3K/Akt-FoxA1 signalling is essential for generation of FoxA1(+)T(reg) cells
por: Liu, Yawei, et al.
Publicado: (2017)

FOXA1 in prostate cancer
por: Dong, Hui-Yu, et al.
Publicado: (2022)

The chromatin remodeling factor Chd1l is required in the preimplantation embryo
por: Snider, Alyssa C., et al.
Publicado: (2012)

Chromatin remodeling is required for sRNA‐guided DNA elimination in Paramecium
por: Singh, Aditi, et al.
Publicado: (2022)

Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli
por: Qin, Wanhai, et al.
Publicado: (2021)

Direct inhibition of dioxygenases TET1 by the rheumatoid arthritis drug auranofin selectively induces cancer cell death in T-ALL
por: Chen, Long, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_itos3vnkt0jeuq5num8h9sker3