Cargando…

Aptamer-antibody hybrid ELONA that uses hybridization chain reaction to detect a urinary biomarker EN2 for bladder and prostate cancer

We report an EN2-specific (K(d) = 8.26 nM) aptamer, and a sensitive and specific enzyme-linked oligonucleotide assay (ELONA) for rapid and sensitive colorimetric detection of bladder and prostate cancer biomarker EN2 in urine. The assay relies on an aptamer-mediated hybridization chain reaction (HCR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Eunseon, Kang, Minji, Ban, Changill
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263169/ https://www.ncbi.nlm.nih.gov/pubmed/35798816 http://dx.doi.org/10.1038/s41598-022-15556-1

Ejemplares similares

G-quadruplex aptamer targeting Protein A and its capability to detect Staphylococcus aureus demonstrated by ELONA
por: Stoltenburg, Regina, et al.
Publicado: (2016)

Establishment of an Improved ELONA Method for Detecting Fumonisin B(1) Based on Aptamers and Hemin-CDs Conjugates
por: Zhao, Xinyue, et al.
Publicado: (2022)

A Combined ELONA-(RT)qPCR Approach for Characterizing DNA and RNA Aptamers Selected against PCBP-2
por: Moreno, Miguel, et al.
Publicado: (2019)

Aptamers and Their Biological Applications
por: Song, Kyung-Mi, et al.
Publicado: (2012)

Aptamer–nanoparticle complexes as powerful diagnostic and therapeutic tools
por: Jo, Hunho, et al.
Publicado: (2016)

Cationic Surfactant-Based Colorimetric Detection of Plasmodium Lactate Dehydrogenase, a Biomarker for Malaria, Using the Specific DNA Aptamer
por: Lee, Seonghwan, et al.
Publicado: (2014)

Development of a one-shot dual aptamer-based fluorescence nanosensor for rapid, sensitive, and label-free detection of periostin
por: Park, Jonghoon, et al.
Publicado: (2023)

Hybrid Antibody–Aptamer Assay for Detection of Tetrodotoxin in Pufferfish
por: Shkembi, Xhensila, et al.
Publicado: (2021)

Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition
por: Choi, Sung-Jin, et al.
Publicado: (2016)

Phylogeography and historical demography of the Lusitanian snail Elona quimperiana reveal survival in unexpected separate glacial refugia
por: Vialatte, Aude, et al.
Publicado: (2008)

Proximity-dependent initiation of hybridization chain reaction
por: Koos, Björn, et al.
Publicado: (2015)

Grafting from a Hybrid DNA–Covalent Polymer by the Hybridization Chain Reaction
por: Noteborn, Willem E. M., et al.
Publicado: (2018)

Displacement and hybridization reactions in aptamer-functionalized hydrogels for biomimetic protein release and signal transduction
por: Lai, Jinping, et al.
Publicado: (2017)

The Application of Hybridization Chain Reaction in the Detection of Foodborne Pathogens
por: Zhao, Jinbin, et al.
Publicado: (2023)

Troponin Aptamer on an Atomically Flat Au Nanoplate Platform for Detection of Cardiac Troponin I
por: Lee, Hyoban, et al.
Publicado: (2020)

A RNA-DNA Hybrid Aptamer for Nanoparticle-Based Prostate Tumor Targeted Drug Delivery
por: Leach, John C., et al.
Publicado: (2016)

Aptasensor for multiplex detection of antibiotics based on FRET strategy combined with aptamer/graphene oxide complex
por: Youn, Hyungjun, et al.
Publicado: (2019)

Optimizing the hybridization chain reaction-fluorescence in situ hybridization (HCR-FISH) protocol for detection of microbes in sediments
por: Jia, Zeyu, et al.
Publicado: (2021)

An Antibody-Aptamer-Hybrid Lateral Flow Assay for Detection of CXCL9 in Antibody-Mediated Rejection after Kidney Transplantation
por: Seiler, Lisa K., et al.
Publicado: (2022)

Hybridization chain reaction enables a unified approach to multiplexed, quantitative, high-resolution immunohistochemistry and in situ hybridization
por: Schwarzkopf, Maayan, et al.
Publicado: (2021)

Highly Sensitive Multiplex Detection of Molecular Biomarkers Using Hybridization Chain Reaction in an Encoded Particle Microfluidic Platform
por: Rutten, Iene, et al.
Publicado: (2023)

Multiplexed miRNA northern blots via hybridization chain reaction
por: Schwarzkopf, Maayan, et al.
Publicado: (2016)

Three-dimensional DNA nanostructures to improve the hyperbranched hybridization chain reaction
por: Wang, Jing, et al.
Publicado: (2019)

Elucidation of leak-resistance DNA hybridization chain reaction with universality and extensibility
por: Li, Shaofei, et al.
Publicado: (2020)

Modified in situ Hybridization Chain Reaction Using Short Hairpin DNAs
por: Tsuneoka, Yousuke, et al.
Publicado: (2020)

Commentary: “Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer”
por: Evans, Ronise
Publicado: (2017)

Hybridization Chain Reaction-Based Electrochemical Biosensors by Integrating the Advantages of Homogeneous Reaction and Heterogeneous Detection
por: Xia, Ning, et al.
Publicado: (2023)

RECOVERY OF ANTIBODY ACTIVITY FROM INACTIVE HYBRIDS OF H AND L CHAINS
por: Roholt, O. A., et al.
Publicado: (1967)

Characterization of single chain antibody targets through yeast two hybrid
por: Vielemeyer, Ole, et al.
Publicado: (2010)

Construction of an autonomously concatenated hybridization chain reaction for signal amplification and intracellular imaging
por: Wei, Jie, et al.
Publicado: (2017)

Highly sensitive detection of lipopolysaccharides using an aptasensor based on hybridization chain reaction
por: Xie, Peiyan, et al.
Publicado: (2016)

Enhanced detection of expanded repeat mRNA foci with hybridization chain reaction
por: Glineburg, M. Rebecca, et al.
Publicado: (2021)

Biosensing Amplification by Hybridization Chain Reaction on Phase-Sensitive Surface Plasmon Resonance
por: Yang, Ching-Hsu, et al.
Publicado: (2021)

Electrochemical micro-aptasensors for exosome detection based on hybridization chain reaction amplification
por: Zhang, Wenfen, et al.
Publicado: (2021)

Urinary biomarkers of overactive bladder
por: Tian, Xiao-Jun, et al.
Publicado: (2019)

A minimal hybridization chain reaction (HCR) system using peptide nucleic acids
por: Kim, Ki Tae, et al.
Publicado: (2021)

Development of a Novel Tissue Blot Hybridization Chain Reaction for the Identification of Plant Viruses
por: Filardo, Fiona, et al.
Publicado: (2022)

A DNAzyme-enhanced nonlinear hybridization chain reaction for sensitive detection of microRNA
por: Cao, Xiuen, et al.
Publicado: (2023)

Aptamer-Functionalized Hybrid Nanostructures for Sensing, Drug Delivery, Catalysis and Mechanical Applications
por: Vázquez-González, Margarita, et al.
Publicado: (2021)

Urothelial Bladder Cancer Urinary Biomarkers
por: Noon, Aidan P, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hrp50l2kluevrnebjhhg8mfqla