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Precision medicine: In vivo CAR therapy as a showcase for receptor-targeted vector platforms

Chimeric antigen receptor (CAR) T cells are a cancer immunotherapy of extremes. Unprecedentedly effective, but complex and costly to manufacture, they are not yet a therapeutic option for all who would benefit. This disparity has motivated worldwide efforts to simplify treatment. Among the proposed...

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Detalles Bibliográficos
Autores principales: Michels, Alexander, Ho, Naphang, Buchholz, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263322/
https://www.ncbi.nlm.nih.gov/pubmed/35598048
http://dx.doi.org/10.1016/j.ymthe.2022.05.018