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Contribution of Immunoglobulin Enhancers to B Cell Nuclear Organization

B cells undergo genetic rearrangements at immunoglobulin gene (Ig) loci during B cell maturation. First V(D)J recombination occurs during early B cell stages followed by class switch recombination (CSR) and somatic hypermutation (SHM) which occur during mature B cell stages. Given that RAG1/2 induce...

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Detalles Bibliográficos
Autores principales:	Bruzeau, Charlotte, Cook-Moreau, Jeanne, Pinaud, Eric, Le Noir, Sandrine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263370/ https://www.ncbi.nlm.nih.gov/pubmed/35812441 http://dx.doi.org/10.3389/fimmu.2022.877930

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