Recent Insight on Regulations of FBXW7 and Its Role in Immunotherapy

SCF(FBXW7) E3 ubiquitin ligase complex is a crucial enzyme of the ubiquitin proteasome system that participates in variant activities of cell process, and its component FBXW7 (F-box and WD repeat domain–containing 7) is responsible for recognizing and binding to substrates. The expression of FBXW7 i...

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Detalles Bibliográficos
Autores principales: Xing, Liangliang, Xu, Leidi, Zhang, Yong, Che, Yinggang, Wang, Min, Shao, Yongxiang, Qiu, Dan, Yu, Honglian, Zhao, Feng, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263569/
https://www.ncbi.nlm.nih.gov/pubmed/35814468
http://dx.doi.org/10.3389/fonc.2022.925041

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