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Emergence of the CD226 Axis in Cancer Immunotherapy

In recent years, a set of immune receptors that interact with members of the nectin/nectin-like (necl) family has garnered significant attention as possible points of manipulation in cancer. Central to this axis, CD226, TIGIT, and CD96 represent ligand (CD155)-competitive co-stimulatory/inhibitory r...

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Detalles Bibliográficos
Autores principales: Conner, Michael, Hance, Ken W., Yadavilli, Sapna, Smothers, James, Waight, Jeremy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263721/
https://www.ncbi.nlm.nih.gov/pubmed/35812451
http://dx.doi.org/10.3389/fimmu.2022.914406