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Engineered exosomes for targeted delivery of miR-187-3p suppress the viability of hemangioma stem cells by targeting Notch signaling

BACKGROUND: Infantile hemangioma (IH) is the most common benign vascular tumor of infancy and is proposed to arise from hemangioma stem cells (HemSCs). Therapies for IH include oral beta-blockers, surgery, and the delivery of novel therapeutic agents, such as bioactive microRNAs (miRNAs). However, i...

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Detalles Bibliográficos
Autores principales: Zhao, Ze-Liang, Liu, Chao, Wang, Qi-Zhang, Wu, Hai-Wei, Zheng, Jia-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263766/
https://www.ncbi.nlm.nih.gov/pubmed/35813344
http://dx.doi.org/10.21037/atm-21-4138

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