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Transcriptome sequencing analysis revealed the molecular mechanism of podoplanin neutralization inhibiting ischemia/reperfusion-induced microglial activation

BACKGROUND: Anti-podoplanin antibody (α-PDPN, clone 8.1.1) reduces microglia-mediated inflammation and decreases cerebral infarct volume in mice with stroke. However, the molecular mechanism by which this occurs is unknown. This study sought to systematically analyze the molecular mechanism of α-PDP...

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Detalles Bibliográficos
Autores principales:	Qian, Shuang, Qian, Lei, Yang, Ye, Cui, Jie, Zhao, Yiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263778/ https://www.ncbi.nlm.nih.gov/pubmed/35813319 http://dx.doi.org/10.21037/atm-22-1952

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