Upper airway gene expression shows a more robust adaptive immune response to SARS-CoV-2 in children

Unlike other respiratory viruses, SARS-CoV-2 disproportionately causes severe disease in older adults whereas disease burden in children is lower. To investigate whether differences in the upper airway immune response may contribute to this disparity, we compare nasopharyngeal gene expression in 83...

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Detalles Bibliográficos
Autores principales: Mick, Eran, Tsitsiklis, Alexandra, Spottiswoode, Natasha, Caldera, Saharai, Serpa, Paula Hayakawa, Detweiler, Angela M., Neff, Norma, Pisco, Angela Oliveira, Li, Lucy M., Retallack, Hanna, Ratnasiri, Kalani, Williamson, Kayla M., Soesanto, Victoria, Simões, Eric A. F., Smith, Christiana, Abuogi, Lisa, Kistler, Amy, Wagner, Brandie D., DeRisi, Joseph L., Ambroggio, Lilliam, Mourani, Peter M., Langelier, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263813/
https://www.ncbi.nlm.nih.gov/pubmed/35803954
http://dx.doi.org/10.1038/s41467-022-31600-0

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