Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccharide vaccine on pneumococcal colonisation using the experimental human pneumococcal challenge model in healthy adults (PREVENTING PNEUMO 2)

INTRODUCTION: Despite widely available vaccinations, Streptococcus pneumoniae (SPN) remains a major cause of morbidity and mortality worldwide, causing community-acquired pneumonia, meningitis, otitis media, sinusitis and bacteraemia. Here, we summarise an ethically approved protocol for a double-bl...

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Detalles Bibliográficos
Autores principales: Liatsikos, Konstantinos, Hyder-Wright, Angela, Pojar, Sherin, Chen, Tao, Wang, Duolao, Davies, Kelly, Myerscough, Christopher, Reine, Jesus, Robinson, Ryan E, Urban, Britta, Mitsi, Elena, Solorzano, Carla, Gordon, Stephen B, Quinn, Angela, Pan, Kaijie, Anderson, Annaliesa S, Theilacker, Christian, Begier, Elizabeth, Gessner, Bradford D, Collins, Andrea, Ferreira, Daniela M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263934/
https://www.ncbi.nlm.nih.gov/pubmed/35798520
http://dx.doi.org/10.1136/bmjopen-2022-062109

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