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Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis
BACKGROUND: Aortic diseases in some orphan rheumatological diseases require medical, surgical or peripheral endovascular intervention because they can be catastrophic. Objectives: to analyze the main clinical and epidemiological characteristics of patients with Takayasu arteritis (TA), Marfan syndro...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264075/ https://www.ncbi.nlm.nih.gov/pubmed/35813724 http://dx.doi.org/10.21037/jtd-21-1523 |
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author | Soto, Maria Elena Saucedo-Orozco, Huitzilihuitl Ochoa-Hein, Eric Eid-Lidt, Guering Anaya-Ayala, Javier E. Pérez-Torres, Israel Koretzky, Solange Gabriela Reyes, Pedro A. Espinoza-Saquicela, Edison Ricardo Hernandez, Ivan Martinez-Hernandez, Humberto |
author_facet | Soto, Maria Elena Saucedo-Orozco, Huitzilihuitl Ochoa-Hein, Eric Eid-Lidt, Guering Anaya-Ayala, Javier E. Pérez-Torres, Israel Koretzky, Solange Gabriela Reyes, Pedro A. Espinoza-Saquicela, Edison Ricardo Hernandez, Ivan Martinez-Hernandez, Humberto |
author_sort | Soto, Maria Elena |
collection | PubMed |
description | BACKGROUND: Aortic diseases in some orphan rheumatological diseases require medical, surgical or peripheral endovascular intervention because they can be catastrophic. Objectives: to analyze the main clinical and epidemiological characteristics of patients with Takayasu arteritis (TA), Marfan syndrome (MS) and similar conditions that were treated with cardiothoracic surgery and peripheral endovascular intervention. METHODS: Retrospective and descriptive cohort study that included patients of any age and gender with TA (as per the criteria of the American College of Rheumatology and EULAR/PRINTO), MS (according to Ghent criteria), and similar conditions who underwent cardiothoracic surgery or peripheral endovascular intervention. Data were collected from electronic charts. RESULTS: A total of 77 patients with TA and 135 patients with MS and similar conditions were included. The frequency of surgical or interventional requirements in patients with TA and MS/similar conditions was 77/364 (21.2%) and 135/300 (45%), respectively; such patients were followed for a median of 6 [2–12] and 3.29 (0.42–6.62) years, with (maximum follow-up range of 47 and 21.37 years, respectively). Aneurysms were present in 11 (14.3%) and 66 (48.9%) in patients with TA and MS/similar conditions, respectively. Aortic, mitral and tricuspid valve damage occurred in 8 (10.4%) patients, 4 (5.2%) patients and 1 (1.3%) patient with TA, respectively; corresponding frequencies in patients with MS/similar conditions were 98 (72.6%), 50 (37.0%) and 20 (14.8%). We identified that 20% of patients with TA died after 5.08 years (95% CI: 0.23–25.42 years) and 20 % of the patients with MS and other similar conditions died after 7.52 years (95% CI: 1.10–9.02 years). CONCLUSIONS: The frequency of surgical intervention was low in this study. Long-term prognosis is good if surgery is performed in a timely manner. Epidemiological studies provide relevant information for public health decisions related to the management of orphan rheumatological diseases. |
format | Online Article Text |
id | pubmed-9264075 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-92640752022-07-09 Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis Soto, Maria Elena Saucedo-Orozco, Huitzilihuitl Ochoa-Hein, Eric Eid-Lidt, Guering Anaya-Ayala, Javier E. Pérez-Torres, Israel Koretzky, Solange Gabriela Reyes, Pedro A. Espinoza-Saquicela, Edison Ricardo Hernandez, Ivan Martinez-Hernandez, Humberto J Thorac Dis Original Article BACKGROUND: Aortic diseases in some orphan rheumatological diseases require medical, surgical or peripheral endovascular intervention because they can be catastrophic. Objectives: to analyze the main clinical and epidemiological characteristics of patients with Takayasu arteritis (TA), Marfan syndrome (MS) and similar conditions that were treated with cardiothoracic surgery and peripheral endovascular intervention. METHODS: Retrospective and descriptive cohort study that included patients of any age and gender with TA (as per the criteria of the American College of Rheumatology and EULAR/PRINTO), MS (according to Ghent criteria), and similar conditions who underwent cardiothoracic surgery or peripheral endovascular intervention. Data were collected from electronic charts. RESULTS: A total of 77 patients with TA and 135 patients with MS and similar conditions were included. The frequency of surgical or interventional requirements in patients with TA and MS/similar conditions was 77/364 (21.2%) and 135/300 (45%), respectively; such patients were followed for a median of 6 [2–12] and 3.29 (0.42–6.62) years, with (maximum follow-up range of 47 and 21.37 years, respectively). Aneurysms were present in 11 (14.3%) and 66 (48.9%) in patients with TA and MS/similar conditions, respectively. Aortic, mitral and tricuspid valve damage occurred in 8 (10.4%) patients, 4 (5.2%) patients and 1 (1.3%) patient with TA, respectively; corresponding frequencies in patients with MS/similar conditions were 98 (72.6%), 50 (37.0%) and 20 (14.8%). We identified that 20% of patients with TA died after 5.08 years (95% CI: 0.23–25.42 years) and 20 % of the patients with MS and other similar conditions died after 7.52 years (95% CI: 1.10–9.02 years). CONCLUSIONS: The frequency of surgical intervention was low in this study. Long-term prognosis is good if surgery is performed in a timely manner. Epidemiological studies provide relevant information for public health decisions related to the management of orphan rheumatological diseases. AME Publishing Company 2022-06 /pmc/articles/PMC9264075/ /pubmed/35813724 http://dx.doi.org/10.21037/jtd-21-1523 Text en 2022 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Original Article Soto, Maria Elena Saucedo-Orozco, Huitzilihuitl Ochoa-Hein, Eric Eid-Lidt, Guering Anaya-Ayala, Javier E. Pérez-Torres, Israel Koretzky, Solange Gabriela Reyes, Pedro A. Espinoza-Saquicela, Edison Ricardo Hernandez, Ivan Martinez-Hernandez, Humberto Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis |
title | Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis |
title_full | Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis |
title_fullStr | Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis |
title_full_unstemmed | Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis |
title_short | Cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis |
title_sort | cardiothoracic surgery and peripheral endovascular intervention in cardiovascular damage from a cohort of orphan rheumatological diseases—epidemiological and survival analysis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264075/ https://www.ncbi.nlm.nih.gov/pubmed/35813724 http://dx.doi.org/10.21037/jtd-21-1523 |
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