Clinical outcomes and immune phenotypes associated with STK11 co-occurring mutations in non-small cell lung cancer

BACKGROUND: STK11 mutation in non-small cell lung cancer (NSCLC) is associated with worse survival as well as primary resistance to PD-1/PD-L1 targeting immunotherapy. We hypothesize that co-occurring mutations and tumor mutation burden (TMB) may impact response to therapy and prognosis. METHODS: Fo...

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Detalles Bibliográficos
Autores principales: Malhotra, Jyoti, Ryan, Brid, Patel, Malini, Chan, Nancy, Guo, Yanxiang, Aisner, Joseph, Jabbour, Salma K., Pine, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264081/
https://www.ncbi.nlm.nih.gov/pubmed/35813711
http://dx.doi.org/10.21037/jtd-21-1377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264081/
https://www.ncbi.nlm.nih.gov/pubmed/35813711
http://dx.doi.org/10.21037/jtd-21-1377

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