Moricizine prevents atrial fibrillation by late sodium current inhibition in atrial myocytes

BACKGROUND: Enhanced late sodium current (INaL) is reportedly related to an increased risk of atrial fibrillation (AF). Moricizine, as a widely used anti-arrhythmia drug for suppressing ventricular tachycardia, has also been shown to prevent paroxysmal AF. However, the mechanism of its therapeutic e...

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Detalles Bibliográficos
Autores principales: Zou, Tian, Chen, Qingxing, Chen, Chaofeng, Liu, Guijian, Ling, Yunlong, Pang, Yang, Xu, Ye, Cheng, Kuan, Zhu, Wenqing, Wang, Ru-Xing, Qian, Ling-Ling, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264100/
https://www.ncbi.nlm.nih.gov/pubmed/35813708
http://dx.doi.org/10.21037/jtd-22-534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264100/
https://www.ncbi.nlm.nih.gov/pubmed/35813708
http://dx.doi.org/10.21037/jtd-22-534

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