Quantitative Characterization of Three Carbonic Anhydrase Inhibitors by LESA Mass Spectrometry

[Image: see text] Liquid extraction surface analysis (LESA) coupled to native mass spectrometry (MS) presents unique analytical opportunities due to its sensitivity, speed, and automation. Here, we examine whether this tool can be used to quantitatively probe protein–ligand interactions through calc...

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Detalles Bibliográficos
Autores principales: Illes-Toth, Eva, Stubbs, Christopher J., Sisley, Emma K., Bellamy-Carter, Jeddidiah, Simmonds, Anna L., Mize, Todd H., Styles, Iain B., Goodwin, Richard J. A., Cooper, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264382/
https://www.ncbi.nlm.nih.gov/pubmed/35675480
http://dx.doi.org/10.1021/jasms.2c00024

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