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Method Development and Qualification of pH-Based CEX UPLC Method for Monoclonal Antibodies
Post-translational modifications (“PTMs”) in monoclonal antibodies (mAbs) contribute to charge variant distribution, which will affect biological efficacy and safety. For the characterization of mAbs, charge variants are used as a critical quality attributes for product quality, stability consistenc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264391/ https://www.ncbi.nlm.nih.gov/pubmed/35822792 http://dx.doi.org/10.3390/biotech11020019 |