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Potential genetic robustness of Prnp and Sprn double knockout mouse embryos towards ShRNA-lentiviral inoculation

The Shadoo and PrP prion protein family members are thought to be functionally related, but previous knockdown/knockout experiments in early mouse embryogenesis have provided seemingly contradictory results. In particular, Shadoo was found to be indispensable in the absence of PrP in knockdown analy...

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Detalles Bibliográficos
Autores principales:	Rau, Andrea, Passet, Bruno, Castille, Johan, Daniel-Carlier, Nathalie, Asset, Alexandre, Lecardonnel, Jérome, Moroldo, Marco, Jaffrézic, Florence, Laloë, Denis, Moazami-Goudarzi, Katayoun, Vilotte, Jean-Luc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264527/ https://www.ncbi.nlm.nih.gov/pubmed/35799279 http://dx.doi.org/10.1186/s13567-022-01075-4

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