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Phosphodiesterase 5 inhibitor mirodenafil ameliorates Alzheimer-like pathology and symptoms by multimodal actions

BACKGROUND: Alzheimer’s disease (AD) pathology is associated with complex interactions among multiple factors, involving an intertwined network of various signaling pathways. The polypharmacological approach is an emerging therapeutic strategy that has been proposed to overcome the multifactorial na...

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Detalles Bibliográficos
Autores principales:	Kang, Byung Woo, Kim, Fred, Cho, Joon-Yong, Kim, SangYun, Rhee, Jinseol, Choung, Jai Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264543/ https://www.ncbi.nlm.nih.gov/pubmed/35804462 http://dx.doi.org/10.1186/s13195-022-01034-3

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