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Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance

BACKGROUND: Immune checkpoint blockade (ICB) therapy has revolutionized the treatment of lung squamous cell carcinoma (LUSC). However, a significant proportion of patients with high tumour PD-L1 expression remain resistant to immune checkpoint inhibitors. To understand the underlying resistance mech...

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Detalles Bibliográficos
Autores principales:	Yang, Minglei, Lin, Chenghao, Wang, Yanni, Chen, Kang, Zhang, Haiyue, Li, Weizhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264601/ https://www.ncbi.nlm.nih.gov/pubmed/35799269 http://dx.doi.org/10.1186/s13073-022-01079-x

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