Cargando…

Circular dorsal ruffles disturb the growth factor-induced PI3K-AKT pathway in hepatocellular carcinoma Hep3B cells

BACKGROUND: Circular dorsal ruffles (CDRs) are rounded membrane ruffles induced on the dorsal surfaces of cells stimulated by growth factors (GF). They can serve as signal platforms to activate AKT protein kinase. After GF stimulation, phosphatidylinositol 3-kinase (PI3K) generates phosphatidylinosi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Xiaowei, Liu, Yujie, Zhou, Shuheng, Wang, Li, Wei, Jinzi, Hua, Rui, Shen, Zhongyang, Yoshida, Sei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264614/ https://www.ncbi.nlm.nih.gov/pubmed/35799301 http://dx.doi.org/10.1186/s12964-022-00911-6

Ejemplares similares

Dynamics of Actin Waves on Patterned Substrates: A Quantitative Analysis of Circular Dorsal Ruffles
por: Bernitt, Erik, et al.
Publicado: (2015)

Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
por: Bernitt, Erik, et al.
Publicado: (2017)

Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration
por: Gu, Zhizhan, et al.
Publicado: (2011)

Correction: Dynamics of Actin Waves on Patterned Substrates: A Quantitative Analysis of Circular Dorsal Ruffles
Publicado: (2015)

ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5
por: Hasegawa, Junya, et al.
Publicado: (2012)

Regulation of circular dorsal ruffles, macropinocytosis, and cell migration by RhoG and its exchange factor, Trio
por: Valdivia, Alejandra, et al.
Publicado: (2017)

Correlative Light and Electron Microscopy Reveals the HAS3-Induced Dorsal Plasma Membrane Ruffles
por: Rilla, Kirsi, et al.
Publicado: (2015)

p53 Down Regulates PDGF-Induced Formation of Circular Dorsal Ruffles in Rat Aortic Smooth Muscle Cells
por: Payne, Laura J., et al.
Publicado: (2014)

SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain
por: Hasegawa, Junya, et al.
Publicado: (2011)

A growth factor signaling cascade confined to circular ruffles in macrophages
por: Welliver, Timothy P., et al.
Publicado: (2012)

Energetics of Saddling versus Ruffling in Metalloporphyrins: Unusual Ruffled Dodecasubstituted Porphyrins
por: Conradie, Jeanet, et al.
Publicado: (2017)

c-Abl, Lamellipodin, and Ena/VASP Proteins Cooperate in Dorsal Ruffling of Fibroblasts and Axonal Morphogenesis
por: Michael, Magdalene, et al.
Publicado: (2010)

Palmitoylation regulates vesicular trafficking of R-Ras to membrane ruffles and effects on ruffling and cell spreading
por: Wurtzel, Jeremy G.T., et al.
Publicado: (2012)

Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway
por: Hwangbo, Hyun, et al.
Publicado: (2020)

Avian influenza: Are our feathers ruffled?
por: Balkhy, Hanan, et al.
Publicado: (2006)

Actin-binding Protein-1 Interacts with WASp-interacting Protein to Regulate Growth Factor-induced Dorsal Ruffle Formation
por: Cortesio, Christa L., et al.
Publicado: (2010)

CR3 ruffles FcγR’s claim over phagocytic cups
por: Frautschy, S.A.
Publicado: (2021)

Production of a unique antibody specific for membrane ruffles and its use to characterize the behavior of two distinct types of ruffles
Publicado: (1993)

A tent pole twist on membrane ruffles
por: Philip, Reuben V., et al.
Publicado: (2018)

Macropinosome formation by tent pole ruffling in macrophages
por: Condon, Nicholas D., et al.
Publicado: (2018)

Avian influenza should be ruffling our feathers
por: The Lancet Neurology
Publicado: (2004)

Apoptotic Effects of Xanthium strumarium via PI3K/AKT/mTOR Pathway in Hepatocellular Carcinoma
por: Kim, Juyoung, et al.
Publicado: (2019)

Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival
por: Xu, Bin, et al.
Publicado: (2014)

A new protein of adhesion plaques and ruffling membranes
Publicado: (1983)

Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes
por: Bohdanowicz, Michal, et al.
Publicado: (2013)

Knockdown of the Sonic Hedgehog (SHH) Gene Inhibits Proliferation of Hep3B and SMMC-7721 Hepatocellular Carcinoma Cells via the PI3K/Akt/PCK1 Signaling Pathway
por: Chen, Youping, et al.
Publicado: (2019)

Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma
por: Sun, Eun Jin, et al.
Publicado: (2021)

Hyperphosphorylated FAK Delocalizes from Focal Adhesions to Membrane Ruffles
por: Hamadi, Abdelkader, et al.
Publicado: (2010)

Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway
por: Huang, Yun, et al.
Publicado: (2020)

Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways
por: Wang, Yu, et al.
Publicado: (2016)

NCAPG Promotes The Proliferation Of Hepatocellular Carcinoma Through PI3K/AKT Signaling
por: Gong, Chengwu, et al.
Publicado: (2019)

Tollip promotes hepatocellular carcinoma progression via PI3K/AKT pathway
por: Huang, Lu, et al.
Publicado: (2022)

The Role of PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma Metabolism
por: Tian, Ling-Yu, et al.
Publicado: (2023)

Targeting EGFR/PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma
por: Bang, Jieun, et al.
Publicado: (2023)

$\Delta$ isobar production in the $^{4}Hep\to^{3}Hpn\pi^{+}$ reaction
por: Glagolev, V V, et al.
Publicado: (1997)

YBX3 Mediates the Metastasis of Nasopharyngeal Carcinoma via PI3K/AKT Signaling
por: Fan, Xiaoqin, et al.
Publicado: (2021)

Phosphorylation of p130Cas initiates Rac activation and membrane ruffling
por: Sharma, Alok, et al.
Publicado: (2008)

Contact formation during fibroblast locomotion: involvement of membrane ruffles and microtubules
Publicado: (1988)

Regulation of Cell Contraction and Membrane Ruffling by Distinct Signals in Migratory Cells
por: Cheresh, David A., et al.
Publicado: (1999)

Rac1 activation can generate untemplated, lamellar membrane ruffles
por: Leyden, F., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cmgrbqeb7d2d389v8pqe0ctvgc