Tongxinluo-pretreated mesenchymal stem cells facilitate cardiac repair via exosomal transfer of miR-146a-5p targeting IRAK1/NF-κB p65 pathway

BACKGROUND: Bone marrow cells (BMCs), especially mesenchymal stem cells (MSCs), have shown attractive application prospects in acute myocardial infarction (AMI). However, the weak efficacy becomes their main limitation in clinical translation. Based on the anti-inflammation and anti-apoptosis effect...

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Detalles Bibliográficos
Autores principales: Xiong, Yuyan, Tang, Ruijie, Xu, Junyan, Jiang, Wenyang, Gong, Zhaoting, Zhang, Lili, Ning, Yu, Huang, Peisen, Xu, Jun, Chen, Guihao, Li, Xiaosong, Hu, Mengjin, Xu, Jing, Wu, Chunxiao, Jin, Chen, Li, Xiangdong, Qian, Haiyan, Yang, Yuejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264662/
https://www.ncbi.nlm.nih.gov/pubmed/35799283
http://dx.doi.org/10.1186/s13287-022-02969-y

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